“2016-E”is scored for flute, clarinet (doubling bass clarinet), violin and cello, and was written in 2016 for the Uroboros Ensemble, directed by Gwyn Pritchard. It lasts nine minutes. Clarke′s compositions are either ′Untitled′ or are given a number, which is the year of composition, and a code letter. The composer has said, "The purpose of music is to reach parts of the brain, parts of our experience of perception, which can evaluate and appreciate matters in ways beyond the capacity and realm of words. The listener is invited to form his or her own understanding of the musical work. A musical composition, like an abstract work of visual art, should be allowed to speak for itself."